Areas of work
The thread running through it: methodology applied to questions where the standard approach serves the clinician poorly.
-
Acute ischaemic stroke
Clinical and outcome research in hyperacute stroke care — patient selection, treatment timing, and the real-world performance of acute pathways. -
Endovascular therapy
Decision-making and outcomes in mechanical thrombectomy, including the harder edges of patient selection where the evidence is still maturing. -
Neurosonology
Ultrasound assessment of the cerebral and cervical vasculature — diagnosis, monitoring, and its role in the stroke work-up. -
Bayesian re-analysis of stroke trials
Revisiting stroke-trial data with Bayesian methods to extract more honest, decision-relevant inference from results that frequentist analysis can leave ambiguous.
Why the methodological angle matters
Stroke trials are expensive, hard to run, and frequently end "negative" or "inconclusive" under a frequentist lens — even when they carry real, usable signal. Bayesian re-analysis asks a different and often more clinically honest question: given this evidence, how probable is benefit, and for whom? That framing is not an academic preference; it changes how the result translates to the bedside. It is the same conviction that runs through Livetextbook — organise the evidence so the decision is better supported.
Selected publications
A selection of recent peer-reviewed work — full list on PubMed.
-
Eur J Neurol · 2026
Clinical significance of microembolic signal detection in acute ischemic stroke: insights into ongoing cerebral embolization and occult etiologies. DOI → -
Eur Stroke J · 2026
Prehospital blood pressure lowering in acute hemorrhagic stroke: a systematic review and meta-analysis of randomized controlled trials. DOI → -
Int J Stroke · 2025
Stroke mortality in Greece (2001–2021): trends, sex differences, and the impact of population aging. DOI → -
Neurology · 2025
Endovascular treatment in acute ischemic stroke due to occlusion of medium or distal vessels: a systematic review and meta-analysis. DOI → -
Neurology · 2025
Stroke despite anticoagulation: optimizing rather than switching. DOI → -
Eur Stroke J · 2025
Endovascular therapy versus best medical treatment for symptomatic intracranial atherosclerotic stenosis: a systematic review and meta-analysis. DOI → -
J Clin Med · 2025
Efficacy and safety of intravenous thrombolysis in the extended time window for acute ischemic stroke: a systematic review and meta-analysis. DOI → -
Eur Stroke J · 2025
Fibrinogen time course in acute ischemic stroke patients treated with intravenous thrombolysis with alteplase or tenecteplase. DOI → -
Medicina (Kaunas) · 2025
Tailored treatment of acute ischemic stroke: a narrative review of evidence-based strategies by imaging type and thrombectomy availability. DOI → -
Ther Adv Neurol Disord · 2025
Safety and efficacy of oral anticoagulation in patients with intracranial hemorrhage and atrial fibrillation: a systematic review and meta-analysis of randomized controlled trials. DOI → -
J Clin Med · 2025
Lipoprotein(a) as a stroke biomarker: pathophysiological pathways and therapeutic implications. DOI → -
Neurology · 2024
Tenecteplase vs alteplase in acute ischemic stroke within 4.5 hours: a systematic review and meta-analysis of randomized trials. DOI →
Selected from 100+ indexed publications. Source: PubMed. See the full list →
Current status
- Established peer-reviewed body of work across the areas above
- Ongoing collaborations and active manuscripts
- Selected, linked publication list published (PubMed / DOI)